Authors:
A. S. Krivonogova,
A. G. Isaeva,
O. V. Sokolova,
K. V. Moiseeva
Ural Federal Agrarian Research Center of the Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia
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Abstract. A study of the antibiotic susceptibility of bacteria of the genus Enterobacter, selected at regional dairy enterprises,was carried out. The purpose of this work was to assess the phenotypic resistance profiles of Enterobacterspp. in the loci of fermenal microbiocenoses related to milk production. Research methodology and methods. Inthe course of the work carried out, milk, mammary gland secretions, and udder washes from cows at dairy cattlebreeding enterprises located in different districts of the Ural region were examined. The phenotypic resistance ofEnterobacter spp. Isolates was analyzed to 10 antibacterial drugs: ciprofloxacin, enrofloxacin, ofloxacin, meropenem,doxycycline, chloramphenicol, ceftriaxone, amoxicillin, ampicillin, rifampicin. Results. Average sensitivity valuesof Enterobacter spp. for all surveyed enterprises were at the level of 2.0–3.3 conventional units (at maximum = 4)to target antibiotics, and at the level of 2.0–2.1 conventional units to non-target antibiotics. The highest bactericidalefficacy was found in fluoroquinolones, the lowest in doxycycline and chloramphenicol. For individual enterprises,the average resistance profile included good sensitivity to 3–4 antibiotics, reduced to 4–5 and resistance to 1–2 antibiotics.The main conclusion is that in eight surveyed enterprises, the usual pattern was the resistance of isolates ortheir low sensitivity to several antibiotics of different classes, which indicates an unfavorable situation with AMR.Scientific novelty. The results obtained in the course of the work performed made it possible to assess the currentand actual levels of resistance of Enterobacter spp. Isolates inhabiting those loci of fermenal microbiocenoses thatare directly related to milk production.
Keywords: antimicrobial resistance, antibiotic resistance, enterobacteria, Enterobacter spp., Antibiotics, phenotypicantibiotic sensitivity, resistance profile, animal husbandry, milk.
For citation: Krivonogova A. S., Isaeva A. G., Sokolova O. V., Moiseeva K. V. Profiles of antimicrobial resistance ofenterobacteria isolated at livestock enterprises of the Ural region // Agrarian Bulletin of the Urals. 2021. No. 08 (211).Pp. 36−41. DOI: 10.32417/1997-4868-2021-211-08-36-41.
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