Agrarian Bulletin of the Urals

The journal has been published since 2000

ISSN 1997 - 4868 (Print); ISSN 2307-0005 (Online)

 

A. V. KIM, N. N. KRASOVSKII, V. V. GLUSHENKOVA, ON THE CONTROL OF THE MATHEMATICAL MODEL OF HIV-PROCESS

АuthorsA. V. KIM, doctor of physics and mathematics science, professor,

N. N. KRASOVSKII, doctor of science in physics and mathematics, professor, head of the department,

Ural State Agrarian University (42 K. Libknehta Str., 620075, Ekaterinburg; tel: +7 (343) 371-33-63),

V. V. GLUSHENKOVA, programmer,

Russian Academy of Science, Ural branch, Institute of Mathematics and Mechanics (16 S. Kovalevskaya Str., 620990, Ekaterinburg)

Abstract: Renewed the mathematical model of HIV-process proposed in the research. There is solving the problem of control, the feedback of the model of HIV-processes. The role of the control actions in this model plays the effectiveness of two drugs. The problem of non-linear translation of a managed object from is given initial to a given final state, which is determined by the initial and final values of the image information. As information selects the phase coordinates of the controlled object, de- pends on the number of healthy and infected cells, virus particles and immune effectors. In view of the nonlinear differential equations describing the process of HIV, the problem is solved in the class of mixed management strategies using the method of extremely shift from scientific works. With this as a guide (model-leader) used graphs of system parameters over time from the research. For steady motion tracking real dynamic object model and a guide-used probabilistic control scheme of the re- search. Theoretical results are illustrated by computer simulation of the process with the parameters of the system and the data close to real. These results continue the study of the previous science works.

Keywords: HIV-process, a mathematical model, extreme shift, mixed strategy, model-seeing eye.

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