F. M. Nurgaliev1, O. K. Pozdeev2 , E. I. Semenov3
1 Moscow State Academy of Veterinary Medicine and Biotechnology – MVA named after K. I. Skryabin, Moscow, Russia
2 Kazan State Medical Academy – Branch of the Russian Medical Academy of Continuous Professional Education the Ministry of Healthcare of the Russian Federation, Kazan, Russia
3 Federal Center for toxicological, radiation, and biological safety, Kazan, Russia
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Volume 25 No. 12
Date of paper submission: 30.05.2025, date of review: 30.06.2025, date of acceptance: 28.07.2025.
Published: 12/31/2025
Abstract. In recent years, representatives of the bacterium of the genus Helicobacter have remained the object of research in medicine and veterinary medicine. While the etiological significance of H. pylori in the development of gastroduodenal diseases in humans has been confirmed, the importance of other helicobacter pylori in the development of pathologies in domestic animals has not been sufficiently studied. The circulation of such microorganisms in wild animal populations is even more vague. The purpose of this study was to try to determine the frequency of infection of the gastrointestinal tract with Helicobacter species of wild boars living in the Central Volga region. Methods. Biopsies of the gastric mucosa of 10 wild boars were examined using bacteriological and molecular genetic methods. Also, all samples were subjected to pathomorphological studies for the presence of gastric mucosa. Results. Morphological examination of the gastric mucosa of wild boars revealed gastropathology of varying severity in all stomachs, ranging from moderate hyperkeratosis to severe erosive–ulcerative lesions. Histological evaluation likewise demonstrated diverse pathological alterations in every stomach, with the most pronounced inflammatory changes observed in the fundic region, where a pattern of severe gastritis was recorded in 70% of cases. Microscopic assessment of gastric mucosal impression smears from the fundic region of two stomachs showed tightly coiled, spiral-shaped Gram‑negative rods typical of bacteria of the genus Helicobacter. Molecular analysis identified H. suis DNA (16S rRNA, 150 bp) in one animal and a combination of H. pylori (23S rRNA, 267 bp) and H. rappini (ureB, 101 bp) DNA in another. These findings suggest that wild boars may act as a potential reservoir of bacteria of the genus Helicobacter in the Republics of Bashkortostan, Tatarstan and Mari El, which is relevant for assessing infection risks and designing preventive measures for domestic pigs in outdoor production systems. Scientific novelty. For the first time, a comprehensive investigation of the prevalence of bacteria of the genus Helicobacter in wild boars inhabiting the Central Volga region (the Republics of Bashkortostan, Tatarstan and Mari El) was carried out using an integrated approach that combined pathomorphological, histological, microbiological and molecular‑genetic diagnostic methods.
Keywords: Helicobacter species, wild boars, zoonoses, laboratory diagnostics, gastritis
Acknowledgements. The study was carried out at the expense of a grant from the Academy of Sciences of the Republic of Tatarstan, provided to young candidates of sciences (postdoctoral fellows) for the purpose of defending their doctoral dissertation, performing research, as well as performing labor functions in scientific and educational organizations of the Republic of Tatarstan within the framework of the State Program of the Republic of Tatarstan “Scientific and Technological Development of the Republic of Tatarstan”.
For сitations: Nurgaliev F. M., Pozdeev O. K., Semenov E. I. Indication and identification of bacteria of the genus Helicobacter in wild boars (Sus scrofa). Agrarian Bulletin of the Urals. 2025; 25 (12): 2173‒2183. https://doi.org/10.32417/1997-4868-2025-25-12-2173-2183 (In Russ.)
Download the full text of the article
