Authors:
A. S. Krivonogova,
A. G. Isaeva,
I. M. Donnik,
E. A. Loginov,
K. V. Moiseeva
Ural State Agrarian University, Ekaterinburg, Russia
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract. The study of phytobiotics application is one of the topical directions in the strategy of antimicrobial resistance containment. The aim of this work was to study the effects of separate and combined use of enrofloxacin and phytobiotic drugs in 400-day-old laying hens. Methods. The studies were conducted on four groups of Loman-classic layers; in the course of the experiment, enrofloxacin and a phytobiotic based on sea buckthorn cake and mustard, cedar and sea buckthorn oils were introduced into the diet. Results. It was found that the use of drugs had no significant effect on the composition of microflora and the level of antibiotic resistance of gastrointestinal bacteria in chickens because by the age of 400 days the intestinal microbiomes of laying hens were already formed, stable and contaminated with AMR agents. Also when combining antibiotic and phytobiotic there was an increase in egg laying rate, average egg weight, accelerated excretion of enrofloxacin from the body of layers and reduction of its content in the egg to the detection limit. While in the group of laying hens receiving only enrofloxacin, its residual content in the egg was detected 2 weeks after cessation of its introduction. Thus, in the course of this research, the most optimal was the combined use of enrofloxacin with a phytobiotic drug, which had the most noticeable positive effect on metabolic parameters, productivity and egg quality. The novelty of the work is to obtain data on the effect of phytobiotic drug on a number of health indicators, productivity of laying hens and egg quality, and the selection of promising scheme of its use.
Keywords: phytobiotic, productivity, laying hens, eggs, resistance genes, antibiotic susceptibility, enrofloxacin, E. coli, opportunistic pathogenic microflora.
For citation: Krivonogova A. S., Isaeva A. G., Donnik I. M., Loginov E. A., Moiseeva K. V. Vliyanie antibiotika i fitobiotika na sostoyaniye zdorov’ya, produktivnost’ kur-nesushek i kachestvo yaytsa [Antibiotic and phytobiotic's effect on health status, productivity of laying hens and egg quality] // Agrarian Bulletin of the Urals. 2023. No. 05 (234). Pp. 61‒71. DOI: 10.32417/1997-4868-2023-234-05-61-71. (In Russian.)
Download the full text of the article
