Authors: K. S. OSTRENKO, candidate of biological sciences, head of laboratory of immunobiotechnology and microbiology, senior researcher, V. P. GALOCHKINA, doctor of biological sciences, senior researcher, laboratory of immunobiotechnology and microbiology, V. A. GALOCHKIN, doctor of biological sciences, professor, leading researcher of the laboratory of immunobiotechnology and microbiology, Institute of Animal Physiology, Biochemistry and Nutrition – Branch of Federal Science Center for Animal Husbandry named after L. K. Ernst (Institute of Animal Physiology, Biochemistry and Nutrition, 249013, Borovsk; phone: +7 484 384-30-26; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.)
Keywords: pregnant sows, lithium ascorbate, lipid-cholesterol metabolism, stress, productivity.
Abstract: The study aims to develop a physiological method for correcting stress and regulating lipid metabolism in pigs. The aim of the work is to develop a new, effective and physiological method to reduce the negative stress impact of any etiology on the processes of ontogenesis and increase productivity. The experiment was conducted on 4 groups of pregnant sows of Irish Landrace breed (3 experimental and 1 control) with 5 heads each. 30 days after the fruitful insemination of the sow, I, II, III groups were daily fed with lithium ascorbate in the form of powder at a dose of 10; 5; 2 mg/kg live weight, respectively. Weighing was carried out before the introduction of the drug. Re-weighing was carried out 2 and 3 months after fertilization and immediately before farrowing. Triacylglycerols, total cholesterol, total protein, lipoprotein fractions – HDL, LDL, and LDL were determined in blood plasma. In the course of the studies it was found that the use of lithium ascorbate feed to pregnant sows at a dosage of 10, 5 and 2 mg/kg body weight, allows to neutralize the negative stress effect and optimize lipid-cholesterol metabolism, which has a beneficial effect on increasing the productivity of pregnant sows. The use of lithium ascorbate in dosages of 10, 5 and 2 mg/kg of live weight allowed to increase the level of HDL in the experimental groups by 43.2; 34.6; 25.7 %, respectively. At the same time in the experimental groups there was a decrease in the concentration of VLDL. So the level of VLDL was lower in the experimental groups by 20.6; 14.7; 5.9 %. The increase in HDL level against the background of LDL reduction indicates a pronounced antiatherogenic effect and a high rate of elimination of free cholesterol from the bloodstream. Introduction, lithium ascorbate on a set of biochemical and physiological parameters confirmed the validity of the proposed concept of the possibility of creating C on its basis of new ways of effective and physiological management of behavioral reactions and correction of stress.
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