Authors:
N. Yu. POPOVA, veterinarian of the department of morphology, examination and surgery,
L. I. DROZDOVA, honored scientist of the russian federation, professor, doctor of veterinary sciences,
Ural State Agrarian University (42 K. Liebknekhta Str., 620075, Ekaterinburg).
Abstract. The article presents the materials of the pathologic anatomical dissection and histological examination of the tissues and organs of the domestic horse (Equus ferus caballus), the Friesian breed, as well as materials from the medical history. A new nosology for this species and breed was first detected in the studied animal, namely, a chronic inflammatory disease of the thyroid gland of autoimmune genesis in the hyperthyroid stage, which caused the development of systemic idiopathic fibrosis. The previously detected nosology was not detected, and also was not described in Russian and foreign literary sources. The article presents materials from the history of the disease with an assessment of the clinical condition of the animal. A description of the pathological and morphological changes in the tissues of the thyroid gland with detected autoimmune thyroiditis, and associated pathological processes in the organs and tissues of the studied animal, as well as a description of the condition associated with thyroiditis, namely, systemic idiopathic fibrosis. Along with this, the peculiarities of the metabolic serum profile of the enzymes, substrates and minerals are presented, the endocrine status of the thyroid gland is assessed by the content of total thyroxin (tT4) and total triiodothyronine (tT3), the content of which was 184.0 nmol/l and 7,9 nmol/l, respectively, as well as data indicating the presence of an autoimmune process in relation to thyroid-type antigens, namely, the level of antibodies to thyroglobulin and antibodies to thyroperoxidase, whose content is set 9.7 IU/ml and 98 IU/ml, respectively.
Keywords: thyroid gland, morphology, horses, autoimmune, thyroiditis.
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