Authors:
E. A. KOSOBOKOV, scientific employee,
T. S. DUDOLADOVA, candidate of biological sciences, senior researcher,
All-Russian Research Institute of Brucellosis and Tuberculosis of Animals (93 Lermontov str., 644001, Omsk).
Abstract. There are analyzes the changes in the internal organs of animals infected with atypical mycobacteria depending on the time of infection. In the literature there are described more than 20 species of atypical mycobacteria that are the cause of mycobacteriosis, however, unlike tuberculosis, they are related to non-pathogenic pathogens. As the elimination of tuberculosis of farm animals the role of non-tuberculosis mycobacteria and mycobacteriosis more and more increases, which are often confused with tuberculosis infection. This is because, under certain conditions non-tuberculosis mycobacteria can be pathogenic properties. The etiological significance of non-tuberculosis mycobacteria are extremely difficult to determine. The analysis of changes in the internal organs of animals infected with atypical mycobacteria depending on the time of infection allows for more detailed monitoring of the development of the pathological process caused by artificial infection of laboratory animals, as well as to identify a clear localization of changes in the organs and tissues. The same method allows to differentially diagnose of pathological processes that occurred at certain periods of infection animals characteristic of the development of certain pathologies. Thus, the researcher displayed a vast information about this kind of infection, which undoubtedly has a beneficial effect on the development of science and allows us to develop new methods of diagnosis, prevention and treatment, as well as an opportunity to improve the old methods and implement them in the work of scientific organizations and animal farms, for a more effective fight against this disease.
Keywords: atypical mycobacteria, guinea pigs, tuberculosis, mycobacteriosis, M. phlei, M. smegmatis, pathogenic changes, infection, antiuberculosis measures, necrotic focus.
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