Authors:
I. V. KIREEV, candidate of biological sciences, associate professor,
V. A. OROBETS, doctor of veterinary sciences, professor, head of department,
Stavropol State Agrarian University (12 Zootechnicheskiy Av., 355017, Stavropol; tel.:+7 652 28-67-44).
Abstract. This article presents the results of testing new anti-stress and antioxidant drugs for lambing and their effect on the parameters of peroxidation and the system of antioxidant protection of the body. It was found that chipping is a powerful stress factor for lambs, which confirms a significant increase in the concentration of cortisol in the blood of animals. After exposure to this stressful situation, a sharp increase in the level of lipid peroxidation products was observed in the experimental animals, which makes it possible to classify these indicators as objective markers of stress. The use of the drug to correct stress conditions in animals has made it possible to achieve a significant decrease in the amount of cortisol in the blood and positively affected the activity of antioxidant enzymes. The introduction of an antioxidant preparation for animals was accompanied by a marked increase in the activity of glutathione peroxidase and catalase, as well as a significant increase in the level of reduced glutathione. The use of these drugs affected the concentration of malonic dialdehyde and diene conjugates in the blood of lambs, which resulted in a decrease in their number in animals receiving medications compared to control animals. Weighing of animals showed that this type of technological stress contributes to a measurable decrease in body weight in lambs, which decreased by 3.8 kg in 14 days after the control in the control group. Preventive administration of the studied drugs allowed to reduce losses of live weight and contributed to higher rates of average daily growth after overcoming the crisis period. Analysis of the results of the experiment showed that the greatest positive effect on all the studied parameters can be obtained with simultaneous application of the developed preparations in the recommended doses.
Keywords: sheep, lambing, stress, cortisol, antioxidant system, lipid peroxidation.
