Аuthors: G. A. GOROSHNIKOVA, graduate student,
L. I. DROZDOVA, doctor of veterinary science, professor, honored scientist of Russia, head of the department,
Ural state agricultural university (42 K. Libknehta Str., 620075, Ekaterinburg; tel: +7 (343) 371-33-63),
A. I. BELOUSOV, leading scientific researcher,
Urals Scientific Research Veterinary Institute (112a Belinsky Str., 620142, Ekaterinburg)
Abstract: White muscle disease (Nutritional myodegeneration) is a degenerative muscle disease found in all large animals. Nutritional myodegeneration (NMD) is an acute, degenerative disease of skeletal muscle caused by a dietary deficiency of selenium or vitamin E in young, rapidly growing calves, lambs. Young, rapidly growing animals usually are affected, although the disease has also been reported in yearling and adult cattle. The disease occurs in many regions of the Russian Federation, including the Sverdlovsk region. Study investigates the features of the metabolic profile of animals in conditions of chronic selenium deficiency. The importance of serum CK activities is in the diagnosis and prognosis of subclinic and clinic white muscle disease in adult cows. Serum CK, activities were significantly higher in cows with subclinical and clinical white muscle disease compared to healthy cows. Damage to skeletal muscle, due to the development of myopathy — progressive muscular dystrophy was recorded in 36.7 % of cows. Animals with signs of a heart fraction of CK (CK-MB) in mature animals are not recorded. Examination of the liver showed that a significant proportion of the animals were recorded signs of disorders of the hepatobiliary system (toxic liver). Mineral metabolism in cows in the conditions of selenium deficiency has been characteristic features. A significant proportion of lactating cows both branches established metabolic signs that the development of osteodystrophy (reduction of inorganic phosphorus and increased activity of alkaline phosphatase) in 20 % of cows in serum total calcium content is reduced. Fairly common cases of hypokalemia in animals: reduction of potassium is less than 2.5 mmol/l.
Keywords: white muscle disease, calves, cows, biochemical blood tests.
